Who Has The Most Home Runs In One Game. Both of the home runs hit by Fernando Tatís in the third inning for the St. Willingham accomplished the feat on July 27 2009 in a game vs the Milwaukee Brewers.
19 rows Writers of Sporting News described hitting four home runs in a single Major League. Josh Willingham of the Washington Nationals is the most recent player to hit two grand slam home runs in one game. Matt Williams is your home run record holder with 43.
It isnt his fault that the 1994 season was only 115 games.
Five home runs in a game has been achieved four times. Josh Willingham of the Washington Nationals is the most recent player to hit two grand slam home runs in one game. There are currently 18 players in Major League Baseball history who have hit four home runs in a single game. On September 25 2001 Richie Sexson and Jeromy Burnitz both hit three home runs for the Milwaukee Brewers in a game against the Arizona Diamondbacks.
